منابع مشابه
Malignant osteopetrosis: hypercalcaemia after bone marrow transplantation
Discussion In this case engraftment was followed by a rapid rise in the calcium concentration, and hypercalcaemia recurred on a number of occasions. A management plan to control the serum calcium concentration during these acute phases and to maintain long term normocalcaemia evolved with experience. In the acute phase the hypercalcaemia seemed to be controlled primarily by a combination of reh...
متن کاملMalignant osteopetrosis: hypercalcaemia after bone marrow transplantation.
A 3 year old girl presented with malignant osteopetrosis, which was treated by allogeneic bone marrow transplantation. Successful engraftment was complicated by prolonged hypercalcaemia, which was controlled by a combination of a bisphosphonate, phosphate infusions, vigorous resalination, and salmon calcitonin. She was alive and well 16 months after the transplant.
متن کاملOsteopetrosis (Marble Bone Disease): A Rare Disease in Children
Osteopetrosis is a group of diseases that affects the growth and remodeling of bone and characterized by over growth and sclerosis of bone, with thickening of the bony cortices, abnormal dental development and narrowing of the marrow cavities throughout the skeleton. It is an uncommon disease of unknown cause. A 5-year-old boy was suffering from infantile (severe form) osteopetrosis with cardia...
متن کاملImportance of neurological assessment before bone marrow transplantation for osteopetrosis.
Neurological complications of malignant infantile osteopetrosis are well recognised; successful bone marrow transplantation, when performed early in life, can prevent or halt some of them. In a subgroup of infants osteopetrosis is associated with primary retinal degeneration and/or generalised neurodegeneration. Bone marrow transplantation, in spite of being successful in correcting the osseous...
متن کاملMild autosomal recessive osteopetrosis: successful treatment with bone marrow transplant.
We describe a 5 1/2 year old boy who was diagnosed with mild autosomal recessive osteopetrosis based on the presence of bony sclerosis, extramedullary haematopoeisis, leukoerythroblastosis and visual impairment who had an allogeneic bone marrow transplant from a matched sibling donor. Conditioning regime was busulphan 16 mg/kg and cyclophosphamide 200 mg/kg. Apart from transient hypercalcaemia,...
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ژورنال
عنوان ژورنال: Journal of Evolution of Medical and Dental Sciences
سال: 2014
ISSN: 2278-4748,2278-4802
DOI: 10.14260/jemds/2014/2431